Fundamental principles of bhaishajya kalpana. The word Bhaishajya Kalpana is composed of two words – Bhaishajya and Kalpana. The word. Bhaishjya kalpana deals with the Basic Ayurvedic pharmaceutics. •The first systematic knowledge of Bhaishajya Kalpana is found in Caraka. Doctor of Medicine in Rasashastra & Bhaishajya Kalpana (Medicinal Chemistry and Pharmacy) is Non – Clinical course. Keeping with tradition, the course.

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Per-urethral, per-vaginal administration of medicated oils and emulsions. The disease status also plays an important role in deciding the form of the drug. The finer the bhaoshajya, the better is its therapeutic value.

He further elaborates the concept by saying that not a single substance in the Universe is devoid of therapeutic potential and hence is a potential drug source, provided it is used judiciously at appropriate indications.

Powder of each drug is weighed separately and mixed thoroughly. The quantity of water required to be added and to be retained after boiling varies from plant to plant. The paaka is categorized in to mridu soft – if the paste is waxy when rolled between fingers, madhyama moderate if the paste is hard and fires without cracking noise when put in to fire and khara hard if it burns with cracking sound when placed in fire.

After strained decoctions Kwaatha are boiled down, sugar or jiggery is added to it. Choukhambha Sanskrita SanSthaana; This indicates drug preparation and processing methods can influence expression of pharmacological activity.

The Ayurvedic formulations range widely from freshly extracted plant juice to eye drops, ointments, surgical threads etc. This tool needs to be handled judiciously, if not done so it is likely to prove injurious or sometimes fatal to the life of the patient who is receiving it. This can be achieved through specific processing. Some of the plants require specific extraction technique for obtaining expected therapeutic action e.

Ministry of Health and Family Welfare; Paarijaata Nyctanthes arbor-tristis Linn leaves collected in different seasons six samples were subjected to pharmacological evaluation.


Shri Ayurved Mahavidyalaya

The different aspects related to drug formulation, preparation, storage etc. It should not adhere together or become moist.

Severity of the disease invites use of concentrated drug forms. The contents are then subjected to heating to retain one fourth of the water. The ideal condition of the medicated oil is attained when uniform froth comes out and subsides in case of medicated ghee.

Coorna is a fine powder of drug or drugs. A study carried out by Rajesh Barvaliya on A-Panc a tikta ghrita literally translates as medicated ghee prepared from five drugs having bitter taste principles containing ghee involved preparation of the formulation by three methods and subjecting bhasihajya to comparative study. SataavariiWithania somnifera Linn.

Bhaishajya Kalpanaa – The Ayurvedic Pharmaceutics – An Overview

Two finger thick layer of mud is then applied on the covering of leaves. Asafoetida and salt may also be roasted, powdered and then added. Vati and Gutikas – drug forms prepared in the form of tablet or pills. GuduciHolarrhena antidysenterica Linn. Evaluation for adaptogenic property using forced swimming test showed that only the sample prepared by using Solapur go-ghrita produced significant anti-stress activity while other two samples did not produce similar effect.


The raw materials are collected from different regions of the country. The form which ultimately comes into use by the patient is termed as a drug delivery system or drug dosage form. Mineral and metallic preparations last indefinitely. In Ayurvedic therapeutics, bhakshajya in both forms are used, crude as well as processed and converted into different formulations.

In a study carried out by Sudhir Joshi – Yastimadhu Glycyrrhiza glabra Linn was administered in three formulation forms and subjected to comparative evaluation. The contents are then filtered through a four layered muslin cloth. Different procedures are adopted to prepare bhaishayja dosage form, which is stable for a longer period. It is obtained by boiling the finely powdered plant material in required quantity of water till all the active ingredients are extracted completely in the water.

In this respect bhaiehajya substances are broadly divided in two categories: Avaleha – it is a semi-solid preparation of the drugs meant for licking.

Formulation factors influencing expression of pharmacological activity Though it is generally accepted among the ayurvedic fraternity that drug formulation is very important for ensuring therapeutic efficacy, not much importance is being given to assess or ascertain the impact of changes made in formulation factors on the expression of pharmacological activity.


This is then made into thin sticks of about 2 centimeters in length and dried in shade. In Ayurvedic Formulary of India which can be considered as an authentic source book- twenty one type of drug formulations have been mentioned. Tinospora cordifolia Thunb Miers. Such processing is termed as pharmaceutics i. Depending on the requirement, different procedures are adopted to extract therapeutically useful ingredients. A-Panc a tikta ghrita PG-A prepared after ghrita murchanaa a purificatory process and using triphala kalka; PG-B prepared by using ghrita subjected to murchanaa without kalka; PG-C prepared only with plain ghrita without subjecting it to murchanaa and without using kalka.

The plants growing in a graveyard or on a footpath should also not be collected. Though it is generally accepted among the ayurvedic fraternity that drug formulation is very important for ensuring therapeutic efficacy, not much importance is being given to assess or ascertain the impact of changes made in formulation factors on the expression of pharmacological activity.

Administration of cyclophosphamide caused significant suppression in anti-body formation.

Not all but some of the plant ingredients are therapeutically active. Sometimes minerals are also used as ingredients in such cases the mineral is converted to Bhasmas calcined metallic compounds and used as ingredients.

A critical review of Prakara yoga and Pharmaco-clinical study on a combination of certain drugs therein for Vyadhikshamatva effect and Brmhana in children. Considering its importance, different aspects of this discipline have been presented in this review to familiarize the readers, especially those who have just started studying Ayurveda, with concept of ayurvedic pharmaceutics.

When no Anupana is specified such oil should be taken with warm water or warm milk Anonymous,