FARXIGA PI PDF

Get dosing information on FARXIGA® (dapagliflozin), for the treatment of type 2 diabetes mellitus. Visit for more. Forxiga is indicated in adults aged 18 years and older with type 2 diabetes Forxiga can be taken orally once daily at any time of day with or without food. FORXIGA® is a registered trademark of AstraZeneca AB, used under . Monotherapy: FORXIGA (dapagliflozin) is indicated for use as an.

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FARXIGA increases the risk of genital mycotic infections, particularly in patients with prior genital mycotic infections. Talk to your healthcare provider if you experience vaginal odor, white or yellowish vaginal discharge discharge may be lumpy or look like cottage cheeseor vaginal itching Yeast infection of skin around the penis balanitis in men who take FARXIGA.

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Use caution in patients with a history of angioedema to another DPP-4 inhibitor. Serious reactions have been reported in patients treated with saxagliptin, including anaphylaxis, angioedema, and exfoliative skin conditions.

Rare but serious, life-threatening cases have been reported in patients receiving SGLT2 inhibitors including dapagliflozin. Sign up for support The secret to managing type 2 diabetes is to take small steps… and your first step is to sign up now. Centers for Disease Control and Prevention.

EPAR summary for the public: Average reduction with 5 mg alone when starting at a 9. Estimates of diabetes and its burden in the United States, Warnings and Precautions Faexiga Accessed September 18, Patients experienced relief of symptoms upon discontinuation. Cases have been reported in females and males. Some cases were fatal. Serious outcomes have included hospitalization, surgeries, and death. Assess patients who present with signs and symptoms of metabolic acidosis for ketoacidosis, regardless of blood glucose level.

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Type 2 Diabetes Treatment | QTERN® (dapagliflozin and saxagliptin) – For HCPs

The most common side effects farxigw FARXIGA include yeast infections of the vagina or penis, and changes in urination, including urgent need to urinate more often, in larger amounts, or at night. Dapagliflozin versus glipizide as add-on therapy in patients with type 2 diabetes who have inadequate glycemic control with metformin: Long-term glycaemic response and tolerability of dapagliflozin versus a sulphonylurea as add-on therapy to metformin in patients oi type 2 diabetes: Take the Next Step.

FARXIGA is indicated as an adjunct to diet and exercise to improve glycemic control in adults with type 2 diabetes mellitus.

Symptoms may include nausea, tiredness, vomiting, trouble breathing, and abdominal pain. Monitor for hypotension Ketoacidosis has been reported in patients with type 1 and type 2 diabetes receiving dapagliflozin.

Randomized, double-blind trial of fzrxiga therapy with saxagliptin add-on to dapagliflozin plus metformin in patients with type 2 diabetes.

Evaluate for signs and symptoms of UTIs and treat promptly. Advise females of potential risk to a fetus especially during the second and third trimesters Lactation: Effect of dapagliflozin in patients with fwrxiga 2 diabetes who have inadequate glycaemic control with metformin: Use with caution in patients with a history of bladder cancer Severe and Disabling Arthralgia has been reported in patients taking DPP-4 inhibitors.

Talk to your doctor right away if you reduce the amount you eat or drink, or if you lose liquids; for example, from vomiting, diarrhea, or excessive heat exposure Serious urinary tract infections UTIsome that lead to hospitalization, occurred in people taking FARXIGA.

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From the triumvirate to the ominous octet: Dapagliflozin increases serum creatinine and decreases eGFR. If acute kidney injury occurs, discontinue and promptly treat. Elderly patients and patients with impaired renal function may be more susceptible to these changes. In the SAVOR cardiovascular outcomes trial, more patients treated with saxagliptin were hospitalized for heart failure compared to placebo.

Consider other antidiabetic therapies in patients with a history of pancreatitis Hypoglycemia Risk of hypoglycemia is increased when exenatide is coadministered with insulin or insulin secretagogues. Ketoacidosis is a serious condition which may require hospitalization and may lead to death.

Dapagliflozin causes intravascular volume contraction and symptomatic hypotension can occur.

Long-term efficacy of dapagliflozin in patients with type 2 diabetes mellitus receiving high doses of insulin: The pill that starts with. Should not be used to treat type 1 diabetes or diabetic ketoacidosis Use with prandial insulin has not been studied Do not coadminister with other exenatide-containing products Not studied in patients with a history of pancreatitis. J Clin Endocrinol Metab. After initiation, observe patients carefully for symptoms of pancreatitis.

Dapagliflozin increases the risk of genital mycotic infections, particularly in patients with prior genital mycotic infections. QTERN is indicated as an adjunct to diet and exercise to improve glycemic control in adults with type 2 diabetes mellitus T2DM who have inadequate control with dapagliflozin or who are already treated with dapagliflozin and saxagliptin.